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. 2021 Dec 13;9(4):49. doi: 10.3390/proteomes9040049

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Combined abundances (normalized to the average abundance in healthy controls) of the complement fragments from the four different members of the complement family, unadjusted or adjusted for proteinuria. (A) Combined complement factor peptide abundances, unadjusted. (B) Combined complement factor peptide abundances, adjusted for proteinuria. While adjustment for proteinuria induces some changes, the overall distribution is not substantially affected. Abbreviations: ADPKD: Autosomal dominant polycystic kidney disease; AKI: Acute Kidney Injury; Amyl: Amyloidosis; C3G: C3 glomerulopathy; CAKUT: Congenital anomalies of the kidney and urinary tract; DKD: Diabetic kidney disease; DM: Diabetes Mellitus; FS: Fanconi syndrome; FSGS: focal segmental glomerulosclerosis; HC: Healthy control; HN: Hypertensive nephrosclerosis; IgAN: IgA nephropathy; LN: lupus nephritis; MCD: minimal change disease; MGN: membranous glomerulonephritis; MPGN: membranoproliferative glomerulonephritis; NTx: Kidney transplantation; SLE: Systemic lupus erythematosus; Vas: Vasculitis.