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. 2021 Dec 14;11(12):868. doi: 10.3390/metabo11120868

Table 2.

Least squares means and 95% confidence intervals of blood metabolites and markers of liver function for low (high efficient; HE) and high (low efficient; LE) residual feed intake (RFI) mid-lactation multiparous dairy cows enrolled in 45-day feed efficiency studies.

RFI Group 3
Item 1 HE LE p-Value
Energy and liver function markers
 BUN, mg/dL 18.4 [13.8, 22.9] 18.1 [13.5, 22.6] 0.72
 Lactate, mg/dL 6.3 [5.3, 7.7] 7.0 [5.8, 8.8] 0.44
 Albumin, g/dL 4.4 [3.9, 4.6] 4.3 [3.9, 4.7] 0.62
 Insulin, µ/L 0.42 [0.33, 0.51] 0.48 [0.32, 0.63] 0.50
 AST, U/L 151.5 [110.6, 192.3] 142.9 [100.6, 185.1] 0.55
 ALT, U/L 29.6 [26.3, 33.0] 32.2 [30.1, 34.3] 0.18
 AST:ALT 5.1 [3.2, 6.9] 4.4 [2.8, 6.0] 0.13
 RQUICKI 2 0.52 [0.45, 0.60] 0.53 [0.45, 0.60] 0.84
Acylcarnitines, µM
 Free carnitine 5.6 [3.5, 7.6] 6.2 [4.1, 8.3] 0.26
 C2-aclycarnitine 2.2 [0.5, 3.9] 2.3 [1.0, 3.7] 0.54
 C3-aclycarnitine 0.9 [0.7,1.1] 1.3 [1.0, 1.6] 0.01
 C4-aclycarnitine 0.24 [0.21, 0.27] 0.33 [0.28, 0.38] 0.01
 C5-aclycarnitine 0.08 [0.02, 0.14] 0.07 [0.03, 0.12] 0.70
 C16-aclycarnitine 0.002 [0.001, 0.005] 0.002 [0.001, 0.005] 0.86
 C18-aclycarnitine 2.4 [1.2, 6.3] 2.3 [1.2, 5.9] 0.88
 C18:1-aclycarnitine 0.24 [0.11, 0.75] 0.17 [0.09, 0.43] 0.16
 C5-DC-acylcarnitine 1.0 [0.6, 2.6] 1.2 [0.6, 3.2] 0.47
 C4-OH-acylcarnitine 0.23 [0.003, 0.80] 0.26 [0.01, 0.86] 0.11

1 BUN = blood urea nitrogen; AST = aspartate aminotransferase; and ALT = alanine aminotransferase. 2 Revised quantitative insulin sensitivity check index (Holtenius and Holtenius, 2007) calculated as: RQUICKI = 1/[log (glucose mg/dL) + log (insulin µIU/mL) + log (non-esterified fatty acids mmol/L)]. 3 HE, n = 18; and LE, n = 18.