Figure 5. Changes From Baseline in PDQ-39 Summary Index Score at Months 12, 24, and 36.

Data shown are mean change in points ± SEM. Quality of life (39-item Parkinson's Disease Questionnaire [PDQ-39]) scores were improved throughout the trial in cohort 2, and at months 12 and 24 in cohort 3. A sensitivity analysis that excluded the participant in cohort 1 who underwent deep brain stimulation resulted in a mean ± SEM change from baseline of −0.6 ± 4.6 points at month 36.