Abstract
The first report of the isolation of adenovirus from a pig was that of Haig et al. in 1964. The virus was isolated from faeces and was serologically different from many of the common human adenoviruses. In Denmark, six strains have been found in organ material from pigs (Rasmussen 1966). In the USA Kasza (1966) isolated an adenovirus from the brain of a pig with encephalitic symptoms, and in West Germany the virus was demonstrated in tissue culture of pig kidney from a group of animals where up to every tenth kidney was found to be infected (Mahnet & Bibrack 1966).
The present study deals with virus strains isolated from non-inoculated cell cultures or from normal or diseased pigs. It includes a serological classification of strains isolated from organ material and a study of the cytopathogenic effect of the viruses in cell cultures of the kidneys and lungs of pig embryos and of the kidneys of bacon pigs and calves.
Sammendrag
Siden 1963 er der i cellekulturer fra nyrer af svin blevet isoleret 12 adenovirusstammer. Fire stammer isoleredes fra fæces af sunde svin, tre stammer fra ikke-inokulerede nyrecellekulturer og fem stammer fra obduktionsmateriale af unge grise, der patologisk-anatomisk viste en viræmisk tilstand. Stammerne kunne inddeles i tre cytopatogene grupper, der var forskellige med hensyn til affinitet til cellekulturer fra embryonalt væv, nyrer af baconsvin og kalve. Der fandtes fire serologisk forskellige typer. I modtagelige cellekulturer udviklede alle serologiske prototyper et ensartet og for adenovirus karakteristisk kernedegenerationsforløb.
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