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. 1965 Mar 1;6(1):1–15. doi: 10.1186/BF03547062

Therapeutic Trials in Dogs with Experimental Hepatitis Contagiosa Canis

Behandlungsversuche an Hunden mit experimenteller H.c.c

Terapiförsök på hundar med experimentell Hepatitis contagiosa canis

Gert Lindblad 1,✉
PMCID: PMC8741129  PMID: 14277184

Abstract

The effect of some substances on the temperature, total leucocyte count, and plasma levels of glutamic-oxaloacetic transaminase, glutamic-pyruvic transaminase, and ornithine carbamyl transferase has been studied in dogs with experimentally produced Hepatitis contagiosa canis. Neither the hyperimmune serum Serasix (Pitman-Moore), nor 1 % prednisolone (AGO), nor 6 % Macrodex® (Pharmacia), nor 10 % Rheomacrodex® (Pharmacia) had any beneficial effect on the course of the disease. Opacity of the cornea arose in all the surviving prednisolone-treated dogs. In a group of normal dogs, treatment with Macrodex and Rheomacrodex led to a rise of the glutamic-oxaloacetic transaminase levels within 24 hours but caused no rise of the ornithine carbamyl transferase levels.

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Footnotes

Supported by grants from “Anslag för främjande av medicinsk forskning vid Veterinärhögskolan”.

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