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. 2021 Dec 31;27(1):249. doi: 10.3390/molecules27010249

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of tetrabromobisphenol A (TBBPA) on spontaneous metamorphosis of Xenopus laevis at the metamorphic climax. (A) Percentages of tadpoles at different stages after a six-day exposure. * indicates a significant difference between TBBPA treatment and the solvent control group (p < 0.05). (B) Immunofluorescence images for telencephalons of NF 63 tadpoles. EdU labeled proliferating cells and migrating cells. Sox2 outlined the ventricle zone. (C) The ratio of EdU positive cells number. The data were normalized by the mean value of the solvent control tadpoles. * indicates a significant difference between TBBPA treatment and the solvent control group (p < 0.05).