Table 3.

Effectiveness of vitamin D supplementation on specific subscales/items of ASD Severity Measures.

First Author (Year)	ASD Severity Measure	Subscales/Items	Before-after Change (Mean Trend)	Between Groups Comparison (p-Value)
Feng (2017) [60]	ABC *	Sensory	Decrease	N/A
		Social skills	Decrease †	N/A
		Body and object use	Decrease †	N/A
		Language	Decrease †	N/A
		Social or self-help	Decrease †	N/A
Javadfar (2020) [58]	ABC-C subscales	Irritability	Decrease †	NS
		Lethargy/social withdrawal	Decrease	NS
		Hyperactivity	Decrease †	NS
		Inappropriate speech	Decrease	NS
		Stereotypic behavior	Decrease	NS
Jia (2019) [65]	ABC *	Sensory	Mostly Decrease *	N/A
		Social skills	Mostly Decrease *	N/A
		Body and object use	Mostly Decrease *	N/A
		Language	Always Decrease *	N/A
		Social or self-help	Mostly Decrease *	N/A
Kerley (2017) [63]	ABC subscales	Irritability	Decrease	NS
		Lethargy/social withdrawal	Decrease	NS
		Hyperactivity	Decrease	NS
		Inappropriate speech	Decrease	NS
		Stereotypic behavior	Decrease	NS
	DD-CGAS	Self-care	Increase	Increase †
		Communication	Increase	NS
		Social behaviour	Increase	NS
		School/academic	Increase	NS
Mazahery (2019) [69]	ABC domains	Irritability	Decrease	Decrease †
		Lethargy/social withdrawal	Decrease	NS
		Hyperactivity	Decrease	Decrease †
		Inappropriate speech	Decrease	NS
		Stereotypic behavior	Decrease	NS
Mazahery (2019) [68]	SRS	Social-communicative functioning	Decrease	NS
		Social awareness	Decrease	NS
		Social cognition	Decrease	NS
		Social communication	Decrease	NS
		Social motivation	Decrease	NS
		repetitive/stereotypic interests and behaviours	Decrease	NS
	SPM	Vision	Decrease	NS
		Hearing	Decrease	NS
		Touch	Decrease	NS
		Taste and smell	Decrease	NS
		Body awareness	Decrease	NS
		Balance and motion	Decrease	NS
		Social participation	Decrease	NS
Saad (2016) [55]	CARS	Relating to people	Decrease †	N/A
		Emotional response	Decrease †	N/A
		Imitation	Decrease †	N/A
		Body use	Decrease †	N/A
		Object use	Decrease †	N/A
		Adaptation to change	Decrease †	N/A
		Listening response	Decrease †	N/A
		Taste, smell, touch	Increase	N/A
		Visual response	Decrease †	N/A
		Fear	Decrease	N/A
		Verbal communication	Decrease	N/A
		Activity level	Decrease	N/A
		Non-verbal communication	Increase	N/A
		Level and consistency of intellectual response	Decrease	N/A
		General impression	Decrease †	N/A
	ABC subscales	Irritability	Decrease †	N/A
		Lethargy/social withdrawal	Decrease †	N/A
		Hyperactivity	Decrease †	N/A
		Inappropriate speech	NS	N/A
		Stereotypic behavior	Decrease †	N/A

* 3 cases, 1 month supplementation, repeated twice. † indicates significant at p < 0.05