Table 2.
Outcome | Difference in Outcome per 1 SD (10.8 nmol/L) of Serum Folate | |||||
---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | ||||
β (95% CI) | p-Value | β (95% CI) | p-Value | β (95% CI) | p-Value | |
Metabolic syndrome score (n = 520) | −0.30 (−0.51 to 0.09) | 0.005 | −0.30 (−0.50 to −0.10) | 0.004 | −0.20 (−0.38 to −0.02) | 0.029 |
Systolic blood pressure (mmHg), (n = 529) | −1.51 (−3.18 to 0.16) | 0.076 | −1.58 (−3.29 to 0.12) | 0.069 | −1.25 (−2.89 to 0.39) | 0.135 |
Diastolic blood pressure (mmHg), (n = 529) | −1.57 (−2.58 to −0.56) | 0.002 | −1.42 (−2.39 to −0.45) | 0.004 | −1.13 (−2.04 to −0.21) | 0.016 |
Fasting blood glucose (mmol/L), (n = 529) | −0.003 (−0.10 to 0.10) | 0.957 | 0.01 (−0.08 to 0.11) | 0.807 | 0.03 (−0.08 to 0.12) | 0.629 |
2-h blood glucose (mmol/L), (n = 522) | −0.01 (−0.17 to 0.15) | 0.865 | 0.01 (−0.15 to 0.18) | 0.881 | 0.02 (−0.15 to 0.19) | 0.809 |
HOMA_IR, (n = 526) | −0.004 (−0.09 to 0.09) | 0.932 | 0.02 (−0.06 to 0.11) | 0.603 | 0.05 (−0.03 to 0.14) | 0.224 |
HDL cholesterol (mmol/L), (n = 520) | 0.03 (0.002 to 0.06) | 0.037 | 0.04 (0.006 to 0.07) | 0.018 | 0.04 (0.01 to 0.07) | 0.023 |
Triglycerides (mmol/L), (n = 520) | 0.0004 (−0.04 to 0.04) | 0.983 | −0.01 (−0.05 to 0.03) | 0.525 | −0.003 (−0.04 to 0.04) | 0.883 |
HOMA-IR, homeostatic model assessment of insulin resistance; β, β-coefficient; CI, confidence interval. Model 1: Unadjusted. Model 2: Adjusted for age, sex, education level, smoking, alcohol intake, residential site. Model 3:Model 2 + body mass index + objectively measured physical activity.