Table 7.
Hematological parameters in normal or hypercholesterolemic Wistar rats after treatment with I. aquifolium and terpenoid fractions.
| Group | p < Value | |||||
|---|---|---|---|---|---|---|
| CON | CHOL | ILEX | TERP | TERPCHOL | ||
| WBC 2 G/L | 6.06 ± 1.38 a,1 | 5.03 ± 0.67 b | 7.26 ± 2.32 b | 5.81 ± 1.48 b | 8.30 ± 1.43 b | <0.001 |
| RBC 3 T/L | 7.63 ± 0.58 a | 8.58 ± 0.35 b,c | 8.18 ± 1.16 b,c | 7.35 ± 0.84 b | 9.72 ± 0.43 b,c | <0.001 |
| HGB 4 mmol/L | 9.23 ± 0.71 a | 9.43 ± 0.25 a | 10.04 ± 1.42 | 8.90 ± 0.97 a | 11.06 ± 0.64 b | <0.001 |
| HCT 5 L/L | 0.41 ± 0.04 a | 0.45 ± 0.01 a | 0.45 ± 0.06 a | 0.39 ± 0.05 a | 0.52 ± 0.03 b | 0.019 |
| MCV 6 fL | 53.56 ± 1.59 a | 52.86 ± 1.07 | 55.13 ± 0.83 b | 53.13 ± 0.99 a | 53.13 ± 1.89 | <0.001 |
| MCH 7 fmoL | 1.21 ± 0.06 a | 1.10 ± 0.03 c | 1.23 ± 0.03 c | 1.21 ± 0.02 c | 1.14 ± 0.03b c | <0.001 |
| MCHC 8 mmol/L | 22.57 ± 0.63 a | 20.87 ± 0.24 c | 22.28 ± 0.40 c | 22.70 ± 0.32 c | 21.48 ± 0.48 b,c | <0.001 |
| PLT 9 G/L | 592.11 ± 65.98 | 615.57 ± 92.54 | 768.25 ± 66.07 | 693.50 ± 96.67 | 552.38 ± 79.09 | 0.039 |
1 Values are mean ± SEM; different letters within a row indicate significant differences between groups (p < 0.05; ANOVA followed by the post-hoc test); 2 white blood cells; 3 red blood cells; 4 hemoglobin; 5 hematocrit; 6 mean corpuscular volume; 7 mean corpuscular hemoglobin; 8 mean corpuscular hemoglobin concentration; 9 platelets.