Table 9.
Effects of I. aquifolium and terpenoids on immunological and antioxidant parameters in normal or hyperlipidemic Wistar rats.
| Group | p < Value | |||||
|---|---|---|---|---|---|---|
| CON | CHOL | ILEX | TERP | TERPCHOL | ||
| IgG 2 g/L | 11.20 ± 2.64 a,1 | 14.01 ± 3.48 | 14.07 ± 4.16 | 12.42 ± 2.95 | 15.73 ± 4.50 b | 0.052 |
| IgM 3 mg/mL | 0.56 ± 0.19 | 0.62 ± 0.15 | 0.73 ± 0.20 a | 0.51 ± 0.13 b | 0.62 ± 0.12 | 0.068 |
| IL-6 4 pg/mL | 37.49 ± 13.67 | 39.71 ± 5.28 | 32.27 ± 5.99 | 26.99 ± 14.86 | 34.99 ± 5.08 | 0.130 |
| IL-10 5 pg/mL | 14.11 ± 9.85 a | 4.05 ± 3.09 b | 14.43 ± 7.34 b | 17.58 ± 5.47 b | 12.85 ± 4.33 b | <0.001 |
| TAS 6 mmol/L | 1.27 ± 0.30 a,c | 0.97 ± 0.05b c | 0.92 ± 0.12 b,c | 1.34 ± 0.06 b | 1.12 ± 0.10 c | <0.001 |
| MDA 7 ng/mL | 104.17 ± 47.78 a | 468.94 ± 44.40 b | 368.28 ± 48.28 b | 81.43 ± 16.86 c | 419.75 ± 69.52 b | <0.001 |
| GPx 8 U/L | 136.55 ± 28.96 | 149.87 ± 38.62 | 129.69 ± 29.22 | 131.99 ± 84.14 | 150.03 ± 23.98 | 0.061 |
| TOS 9 µmol/L | 10.27 ± 6.54 | 8.77 ± 2.02 | 13.29 ± 3.75 | 9.28 ± 3.34 | 10.03 ± 2.79 | 0.086 |
1 Values are mean ± SEM; different letters within a row indicate significant differences between groups (p < 0.05; ANOVA followed by the post-hoc test); 2 immunoglobulin G; 3 immunoglobulin M; 4 interleukin-6; 5 interleukin-10; 6 total antioxidant status; 7 malondialdehyde; 8 glutathione peroxidase; 9 total oxidant status.