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. 2021 Jul 14;218(3):iyab068. doi: 10.1093/genetics/iyab068

Table 5.

Fisher’s exact test reveals that mRNA are less likely to have an eQTL when they correspond to a differentially expressed gene (odds ratio 0.81, 95% CI 0.74–0.88, P <0.001)

Differential expression
mRNA
Yes No eQTL
eQTL Yes 4,045 1,410 48%
No 4,612 1,303 52%
miRNA
Yes No mirQTL
mirQTL Yes 21 8 12%
No 172 42 88%

A stronger but nonsignificant trend is observed with miRNA.