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. 2022 Jan 5;11:e69109. doi: 10.7554/eLife.69109

Figure 7. Changes in expression of some of the key HIF pathway genes in surface fish and cavefish exposed to hypoxia (1 mg/L oxygen) or normoxia.

Figure 7.

Bars indicate qPCR fold difference over surface fish in normoxic condition. Error bars: range of fold change. Asterisks from left to right: p < 0.0001, p < 0.0001, p = 0.0044, p = 0.0306, p = 0.453, p = 0.0155, p = 0.0083, p = 0.0306, p = 0.0002, and p = 0.0003. N = 6 for each determination. Statistics by one-way ANOVA followed by Student’s t-test (igfbp1a, hif1ab, hif1a-like, hif1a-like2, hk1, g6pd, ldha, pdk1) or with unequal variance by Wilcoxon/Kruskal-Wallis Rank Sums test followed by Wilcoxon for each pair (hif1aa).

Figure 7—source data 1. Changes in expression of some of the key HIF pathway genes in surface fish and cavefish exposed to hypoxia (1 mg/L oxygen) or normoxia.