Skip to main content
JAMA Network logoLink to JAMA Network
. 2022 Jan 18;327(3):286. doi: 10.1001/jama.2021.24153

Incorrect Equivalent Dose and P Values in Figure 3

PMCID: PMC8767435  PMID: 35040905

In the Original Investigation titled “Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial,”1 published in the November 9, 2021, issue of JAMA, there was an incorrect equivalent dose listed and incorrect P values in Figure 3. In the second paragraph of the article, the last sentence should have been “Pharmacodynamic studies suggest dose-dependent activation of the corticosteroid receptor with increasing doses up to 60 mg of prednisone (equivalent to 9 mg of dexamethasone).10” In Figure 3, a coding error was recently detected revealing that the majority of P values were incorrect. In the last column of Figure 3, the P values should have been .32 instead of .57; .76 instead of .83; .31 instead of .53; .36 instead of .44; .13 instead of .59; and .25 instead of .64. This article was corrected online.

Reference

  • 1.Munch MW, Myatra SN, Vijayaraghavan BKT, et al. ; COVID STEROID 2 Trial Group . Effect of 12 mg vs 6 mg of dexamethasone on the number of days alive without life support in adults with COVID-19 and severe hypoxemia: the COVID STEROID 2 Randomized Trial. JAMA. 2021;326(18):1807-1817. doi: 10.1001/jama.2021.18295 [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from JAMA are provided here courtesy of American Medical Association

RESOURCES