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British Journal of Cancer logoLink to British Journal of Cancer
. 2021 Dec 20;126(2):311–312. doi: 10.1038/s41416-021-01615-3

Correction: Cancer-associated fibroblast senescence and its relation with tumour-infiltrating lymphocytes and PD-L1 expressions in intrahepatic cholangiocarcinoma

Chuan Lan 1,2,#, Yuki Kitano 1,#, Yo-ichi Yamashita 1, Takanobu Yamao 1, Kiyoshi Kajiyama 3, Tomoharu Yoshizumi 4, Kengo Fukuzawa 5, Keishi Sugimachi 6, Yasuharu Ikeda 7, Hiroshi Takamori 8, Nobutomo Miyanari 9, Masahiko Hirota 10, Hideo Baba 1,
PMCID: PMC8770484  PMID: 34931043

Correction to: British Journal of Cancer 10.1038/s41416-021-01569-6, published online 06 October 2021

The original version of this article unfortunately contained a mistake. There was a misalignment in Fig. 1. In addition, Table 1 is incorrect. The authors apologize for the oversight. The original article has been corrected.

Table 1.

Clinicopathological features and CAV1 expression in CAFs.

Total (n = 158) CAV1 expression in CAFs p value
Negative (n = 80) Positive (n = 78)
Age (yr) 67.3 ± 10.3 65.8 ± 10.7 68.7 ± 9.7 0.080
Sex 0.434
  Male 88 (55.7%) 47 (58.7%) 41 (52.6%)
  Female 70 (44.3%) 33 (41.3%) 37 (47.4%)
BMI 22.8 ± 3.2 22.4 ± 3.3 23.2 ± 3.1 0.117
CEA (ng/mL) 3.0 (0.6–1692) 2.9 (0.6–1692) 3.1 (0.7–150.1) 0.123
CA19-9 (ng/mL) 36.0 (0–74,079) 22.8 (0.1–36,230) 54.1 (0–74,079) 0.001
PLT 19.8 (5.1–296) 19.6 (5.4–159) 20.7 (5.1–296) 0.953
Total bilirubin (mg/dL) 0.7 (0.1–13.4) 0.7 (0.1–1.6) 0.7 (0.2–13.4) 0.548
Albumin (g/dL) 4.1 (2.6–5.1) 4.1 (3.1–5.1) 4.1 (2.6–4.9) 0.615
Tumor size (mm) 39 (1–180) 35 (1–120) 40 (2.5–180) 0.337
pT 0.046
  T0–2 109 (69.0%) 61 (76.3%) 48 (61.5%)
  T3, 4 49 (31.0%) 19 (23.7%) 30 (38.5%)
pN 0.004
  No 128 (81.0%) 72 (90.0%) 56 (71.8%)
  Yes 30 (19.0%) 8 (10.0%) 22 (28.2%)
Operating time (min) 369.9 ± 131.6 385.7 ± 137.6 353.7 ± 123.8 0.126
Blood loss (mL) 467.5 (2–5140) 437.5 (5–2897) 560 (29–5140) 0.105
Differentiation 0.337
  Well/Mod 107 (67.7%) 57 (71.3%) 50 (64.1%)
  Poor 51 (32.3%) 23 (28.7%) 28 (35.9%)
Postoperative chemotherapy 0.523
  No 117 (74.1%) 61 (76.3%) 56 (71.8%)
  Yes 41 (25.9%) 19 (23.7%) 22 (28.2%)

CAV1 caveolin-1, CAFs cancer-associated fibroblasts, BMI body mass index, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9, pT pathological tumor stage, pN pathological nodal stage, Mod moderately, Poor poorly.


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