Table 1.
EMA sepsis scoring system, adapted from EMA publication (2010) and Odabasi and Bulbul (2020) [6,8]. The presence of at least two clinical signs and at least two laboratory findings from the table are considered as clinical sepsis in the context of a suspected or proven infection. This scoring system is suitable for EONS and LONS and is applicable up to 44 weeks of age.
| EMA Sepsis Scoring System | |
|---|---|
| Clinical | Laboratory |
| Body temperature: | Leukocyte count: |
| >38.5 °C or | <4000/mm³ or >20.000/mm³ |
| <36 °C and/or temperature irregularities | Immature/total neutrophil ratio: |
| Cardiovascular instability: | ≥0.2 |
| Bradycardia or tachycardia and/or | Platelet Count: |
| rhythm irregularity | <100.000/mm³ |
| Urine amount < 1 mL/kg/h | CRP: |
| Hypotension | >15 mg/L (1.5 mg/dL) |
| Impaired peripheral perfusion | Procalcitonin: |
| Skin and subcutaneous lesions: | ≥2 ng/mL |
| Petechiae | Blood sugar monitoring (at least twice): |
| Sclerema | Hyperglycemia (>180 mg/dL) |
| Respiratory Instability: | Hypoglycemia (<45 mg/dL) |
| Apnea or | Metabolic acidosis: |
| Tachypnea or | Base deficit >10 mEq/L or |
| Increased oxygen demand or | Serum lactate >2 mmol/L |
| Increased need for ventilation support | |
| Gastrointestinal: | |
| Nutritional intolerance | |
| Insufficient breastfeeding | |
| Abdominal distension | |
| Non-specific: | |
| Irritability | |
| Lethargy | |
| Hypotonia | |