Table 1.
Encapsulation design: Ratio between ingredients of each formula.
| Categories | Formula | Ingredient Ratio | |||||
|---|---|---|---|---|---|---|---|
| SIDI | LEC | CHL | NP | ||||
| Types of first coating layers | NP-based coating | Single wall layer | SIDI-GA | 1 | 0 | 0 | 10 |
| SIDI-MA | |||||||
| SIDI-PE | |||||||
| SIDI-STC | |||||||
| Complex matrix in wall layer | SIDI-GA/STC | 1 | 0 | 0 | 5:5 | ||
| SIDI-PE/STC | |||||||
| Lipid-based coating |
Phytosome (lecithin) | PH-SIDI | 1 | 1 | 0 | 0 | |
| Cholesterol incorporated phytosome | PH/CHL-SIDI | 1 | 1 | 0.5 | 0 | ||
| Secondary coating layers | NP-secondary coating I (PH were coated with NP) |
Single wall layer | PH-SIDI-GA | 1 | 1 | 0.5 | 10 |
| PH-SIDI-MA | |||||||
| PH-SIDI-PE | |||||||
| PH-SIDI-STC | |||||||
| Complex matrix in wall layer | PH-SIDI-GA/STC | 1 | 1 | 0.5 | 5:5 | ||
| PH-SIDI-PE/STC | |||||||
| NP-secondary coating II (PH/CHL were coated with NP) |
Single wall layer | PH/CHL-SIDI-GA | 1 | 1 | 0.5 | 15 | |
| PH/CHL-SIDI-MA | |||||||
| PH/CHL-SIDI-PE | |||||||
| PH/CHL-SIDI-STC | |||||||
| Complex matrix in wall layer | PH/CHL-SIDI-GA/STC | 1 | 1 | 0.5 | 7.5:7.5 | ||
| PH/CHL-SIDI-PE/STC | |||||||
SIDI, enriched fraction of the silverskin extract (SI1) obtained using the DiaionTM HP20LX resin; PH, nano-phytosome; PH/CHL, cholesterol incorporated nano-phytosome; GA, gum Arabic; MA, maltodextrin; PE, pectin; STC, starch; LEC, lecithin (containing 94% phosphatidylcholine); NP, natural polymer.