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. 2021 Dec 10;25(1):103608. doi: 10.1016/j.isci.2021.103608

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© 2021.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Effect of DSSO on KRAS diffusion on POPC/POPS bilayer

(A) Mean-square displacement (MSD) analysis of KRAS4b tracks before DSSO and after addition of DSSO at concentrations ranging from 1 μM up to 10 mM.

(B) Diffusion coefficients of fast (D1, green), intermediate (D2, orange), and slow (D3, red) calculated from HMM analysis before (filled) and after (unfilled) addition of DSSO.

(C) Fractional occupancy of fast (D1, green), intermediate (D2, orange), and slow (D3, red) calculated from HMM analysis in presence of DSSO. Data are represented as mean +/− standard deviation.