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International Journal of Molecular Medicine logoLink to International Journal of Molecular Medicine
. 2022 Jan 4;49(3):25. doi: 10.3892/ijmm.2022.5080

Circular RNA CSNK1G1 promotes the progression of osteoarthritis by targeting the miR-4428/FUT2 axis

Jianwei Xiao, Rongsheng Wang, Weijian Zhou, Xu Cai, Zhizhong Ye
PMCID: PMC8788916  PMID: 34981817

Int J Mol Med 47: 232-242, 2021; DOI: 10.3892/ijmm.2020.4772

Following the publication of the above paper, upon having repeated some of the experiments and contrary to the results reported in the article, the authors have found that the expression of FUT2 did not decrease in the circCSNK1G1 knockdown rat model of osteoarthritis, and furthermore, the expression of FUT2 in the AMO-4428 group was not increased compared with the control group. Moreover, the results of the Bcl-2/BAX experiments assessed by western blot analysis and the percentages of apoptotic cells detected by flow cytometry assay in the 'miR-4428 inhibits chondrocyte apoptosis by targeting FUT2' subsection were performed by an external biotechnology company, and they have not been able to provide the raw data upon the authors submitting a request for these. Therefore, the authors have requested that the paper be retracted on account of a lack of confidence in the presented data.

The Editor of International Journal of Molecular Medicine has agreed with the authors that this paper should be retracted from the Journal. All the authors agree to the retraction of this paper. The Editor and the authors apologize to the readership for any inconvenience caused.


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