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. 2022 Jan 5;11:e72357. doi: 10.7554/eLife.72357

Table 2. Risk factors in relation to mental wellbeing (WEMWBS): differences in mean, variability and skewness estimated by GAMLSS (n = 7,104).

Risk factor % NO distribution BCCG distribution
Mean SD Median COV Skewness*
Female (ref) 52.8% 49.2 8.5 50 0.17 –0.41
Male 47.2% 49.1 8.2 50 0.17 –0.40
 Unadjusted difference, % (SE) –0.2 (0.4) –3.9 (1.7) –0.3 (0.4) –3.5 (1.7) 0.02 (0.11)
 Adjusted difference, % (SE) –0.6 (0.4) –3.6 (1.7) –0.7 (0.4) –2.6 (1.7) 0.00 (0.11)
Non-manual (ref) 34.8% 50.1 7.9 51 0.16 –0.45
Manual social class 65.2% 48.7 8.5 49 0.17 –0.37
 Unadjusted difference, % (SE) –2.8 (0.4) 7.2 (1.8) –2.9 (0.4) 10.9 (1.8) –0.20 (0.12)
 Adjusted difference, % (SE) –2.5 (0.4) 6.0 (1.8) –2.7 (0.4) 9.8 (1.8) –0.24 (0.12)
Physically active (ref) 72.4% 49.9 8.0 51 0.16 –0.38
Inactive 27.6% 47.3 8.9 48 0.19 –0.36
 Unadjusted difference, % (SE) –5.3 (0.5) 10.9 (1.9) –5.2 (0.4) 16.2 (1.9) –0.12 (0.12)
 Adjusted difference, % (SE) –5.3 (0.5) 9.9 (1.9) –5.1 (0.4) 15.2 (1.9) –0.10 (0.12)
*

Skewness is estimated as the Box-Cox power (that is, the power required to transform the outcome to a normal distribution); differences are the absolute difference in Box-Cox power in each subgroup estimated by GAMLSS. GAMLSS estimates multiple distribution moments simultaneously; thus, differences may not exactly correspond to descriptive comparisons reported above.

Estimates mutually adjusted for sex, social class and physical inactivity.

NO: normal distribution; BCCG: Box-Cox Cole and Green distribution: SD: standard deviation; CoV: coefficient of variation; GAMLSS: Generalized Additive Models for Location, Scale and Shape; SE, standard error.