Corrigendum: YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA

In the original article, there was a mistake in Figure 4B as published. The HAEC tubes formation following an incubation with supernatants collected from the YY1 overexpression cells was placed mistakenly using the same image of HUVECs tubes with same treatment in Figure 4B . The mistake was inadvertently introduced in the preparation of revision manuscript. The corrected Figure 4 appears below.

Figure 4.

YY1 stimulated HCC cell culture media accelerated endothelial cells neovascularization. (A) HUVECs and HAECs (red) and HepG2 cells (green) co-cultured in a 1:2 ratio and formed three-dimensional spheroids. Images were taken with a laser scanning confocal microscope, scale bar = 50 μm. (B) Representative image (left) of the formation of HUVECs and HAECs tubes following an incubation with supernatants collected from the indicated cells. Tube formation quantification were analyzed (right). Scale bar = 50 μm. (C) HUVECs and HAECs migration were detected after an incubation with supernatants collected from the indicated cells. (D) HUVECs and HAECs invasion were detected following an incubation with supernatants collected from the indicated cells. Scale bar = 20 μm. (E) WB analyzed pVEGFR2 expression in HUVECs and HAECs treated with conditioned media. (F) Immunofluorescence of pVEGFR2 expression in HUVECs and HAECs treated with conditioned media. Scale bar = 10 μm. *P < 0.05, **P < 0.01.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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