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. 2021 Dec 25;5:38. doi: 10.21037/med-2021-01

Figure 3.

Figure 3

Immunohistochemical features of the normal thymic tissue (A,C,E) and the tumor (B,D,F,G,H). (A,B) Pancytokeratin stain—distribution of positive cells in the tumor (B) was similar to the normal thymus (A). Keratin-positive cells are concentrated at the periphery of cortical areas (cor) and dispersed in medullary regions (med) of the organoid component, while they formed sheets in the lymphocyte-poor component (L-p). (C,D) TdT-expression in immature T-lymphocytes was seen only in cortical areas of the normal thymus (C) and the tumor (D). There was no expression of TdT in lymphocyte-poor component. (E,F) Anti-desmin reaction revealed myoid cells dispersed in medullary regions of the thymus (E), numerous myoid cells were also found in medullary regions (med) of the organoid component and lymphocyte-poor component (L-p). (G,H) Very low Ki-67 index (G) and significant p53-index (H) in lymphocyte-poor epithelial component (A, B: AE1AE3, magnification ×40; C, D: TdT, ×40; E, F: Desmin, ×40; E: Ki-67, ×100; H: p53, ×100).