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. 2022 Jan 14;13(1):1908–1920. doi: 10.1080/21655979.2021.2020396

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Circ_0138959 is abnormally upregulated in periodontitis.

(a) mRNA levels of circ_0099630, circ_0138960, circ_0138959, and circ_0107783 were evaluated by qRT-PCR in three pairs of PDL tissues from patients with periodontitis and healthy controls. (b) qRT-PCR analyses of the expression of circ_0138959 in the PDL tissues obtained from 30 pairs of patients with periodontitis and healthy controls. (c) qRT-PCR analyses of the expression of circ_0138959 in HGFs before and after LPS treatment. (d) mRNA levels of lnc_0138959 and circ_0138959 in HGFs after RNaseR treatment. (e) qRT-PCR analysis of the expression of circ_0138959 and lnc_0138959 in HGFs at the indicated time after treatment with actinomycin D. *P < 0.05, **P < 0.01, ***P < 0.001, vs. healthy, control, mock, and circular groups.