Figure 6.
PSMA knockdown inhibited the proliferation of LNCaP and 22rv1 cells. A. CCK-8 assays were performed to detect the influence of PSMA knockdown on the proliferation of LNCaP and 22rv1 cells. B. EdU assays were performed to assess the influence of PSMA knockdown on the proliferation of LNCaP and 22rv1 cells. C. Colony formation assays were performed to assess the influence of PSMA knockdown on the proliferation of LNCaP and 22rv1 cells. D. 22RV1 cells with stable PSMA silencing were injected subcutaneously into nude mice. After 28 days, the mice were sacrificed, and their tumors were photographed. E. The mice were sacrificed after 28 days, and the tumors were excised and weighed. F. The xenograft tumors were measured every week. Vt = 0.5× Length×Width [2]. (*P < 0.05, **P < 0.01, ***P < 0.001).