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. 2021 Sep 21;12(1):7177–7193. doi: 10.1080/21655979.2021.1979442

Figure 1.

Figure 1.

High APCDD1L-AS1 is discovered in OSCC and correlative to poor prognosis of OSCC patients

(A) APCDD1L-AS1 expression in OSCC tissues and normal tissues was determined by RT-qPCR. (B) The overall survival was analyzed in OSCC patients with high or low APCDD1L-AS1 expression. (C) APCDD1L-AS1 expression was examined in 5-FU-sensitive and 5-FU-resistant OSCC tissues. (D) APCDD1L-AS1 expression was tested in OSCC cell lines (SCC-4, HSC-3, TSCC1, SCC090, and HN-4) and normal human oral keratinocyte cell line (NHOK). (E) APCDD1L-AS1 expression was detected in HSC-3 and HN-4 cells and corresponding 5-FU-resistant cells (HSC-3/5-FU and HN-4/5-FU cells). *P< 0.05, **P < 0.01.