Figure 1.

ZFPM2-AS1 knockdown inhibited the tumorigenesis of glioma. (a) ZFPM2-AS1 expression in glioma tissues and matched control tissues by RT-qPCR. (b) ROC curve analysis was used to assess the diagnostic values of the circCSNK1G1. (c) ZFPM2-AS1 expression in glioma cell lines and control cell line (NHA) by RT-qPCR. (d) RT-qPCR analysis of ZFPM2-AS1 expression in A172 and LN229 cells transfected with sh-ZFPM2-AS1#1 and sh-ZFPM2-AS1#2. (e) CCK-8 assay was performed to detect A172 and LN229 cell viability upon ZFPM2-AS1 knockdown. (f) The proliferation of ZFPM2-AS1-downregulated A172 and LN229 cells was evaluated via colony formation assay. (g) Flow cytometry analysis for cell cycle detection in sh-ZFPM2-AS1#1/2 group or sh-NC group. (h) Cell apoptosis after ZFPM2-AS1 deficiency was testified through TUNEL assay. *p < 0.05, **p < 0.01