Table 2.

Sensitivity, specificity, AUC, and C-index of the classification performance of the three-gene signature in six data sets

GEO accession	TP	FP		FN	TN	Sensitivity (95% CI)	Specificity (95% CI)	AUC (95% CI)	C-index (95% CI)
GSE141512	3		1	3	5	0.500 (0.139–0.860)	0.833 (0.364–0.991)	0.639 (0.311–0.967)	0.639 (0.00788–1.00)
GSE24519	32		0	2	4	0.941 (0.789–0.989)	1.00 (0.395–1.000)	0.978 (0.934–1.00)	0.978 (0.899–1.00)
GSE34198	27		10	22	38	0.551 (0.403–0.691)	0.79 (0.645–0.890)	0.652 (0.542–0.762)	0.652 (0.446–0.857)
GSE48060	24		4	7	17	0.774 (0.584–0.897)	0.809 (0.574–0.937)	0.78 (0.641–0.920)	0.78 (0.501–1.00)
GSE60993	15		1	2	6	0.824 (0.558–0.953)	1.00 (0.561–1.00)	0.882 (0.744–1.000)	0.882 (0.613–1.00)
GSE66360	45		1	4	49	0.918 (0.795–0.973)	0.980 (0.879–0.998)	0.975 (0.948–1.000)	0.975 (0.922–1.00)
GSE109048	14		2	5	17	0.736 (0.485–0.898)	0.894 (0.654–0.981)	0.867 (0.749–0.985)	0.867 (0.635–1.00)