Figure 7.

LINC00511 knockdown suppresses the tumor growth and lung metastasis of GC cells in vivo. A. MGC-803 cells with LINC00511 knockdown or the control cells were inoculated into the mice subcutaneously, respectively, and after the mice were sacrificed, the the tumor weight of the mice was measured (n = 5 in each group). B. Tumor volume of the mice in both groups was measured every 7 days (n = 5 in each group). C. MGC-803 cells with LINC00511 knockdown or the control cells were injected into the mice via tail vain, respectively, and after the mice were sacrificed, the number of metastatic nodules in the lung tissues of the mice was examined (n = 5 in each group). D. H&E staining was used to evaluate the metastasis of MCG-803 cells in the lung tissues sections (scale bar = 25 μm). E. Western blot assay was used to detect the expression of STAT3 in the tumor tissues of both groups

** P < 0.01, and *** P < 0.01.