Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Knockdown of YB-1 suppresses cyclinD1 and upregulates cleaved PARP expression. DU145 and LNCap cells were transfected with a Scramble siRNA or a YB-1 siRNA for 48 h and 72 h. Western blot analysis was performed to assess the expression of YB-1, cyclinD1 and cleaved PARP; GAPDH served as the internal control. A representative image of at least three independent experiments with similar results is shown
