Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 4;12(2):10935–10944. doi: 10.1080/21655979.2021.2000198

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 2. — m⁶A methyltransferase WTAP promoted the stability of DLGAP1-AS1. (a) MeRIP-Seq found that the m⁶A peaks were distributed near stop codon, including the CDS and 3ʹ-UTR of RNA. (b) IGV view software unveiled the possible m⁶A sites on the DLGAP1-AS1. (c) The m⁶A motif of WTAP was AAGGAC. (d) The m⁶A modification sites were located in the 3ʹ-UTR of DLGAP1-AS1. (e) MeRIP-qPCR was performed to detect the m⁶A enrichment of DLGAP1-AS1 precipitated by the m⁶A antibody. (f) m⁶A abundance analysis detected the m⁶A modification level in ADR-resistant BC cells (MCF-7/ADR). (g) RNA stability analysis revealed the stability of DLGAP1-AS1. **P < 0.01 vs control group