Figure 3.

Circ_0090231 knockdown enhances cell viability and suppresses cell injury and pyroptosis in ox-LDL-treated HAECs cells. (a) Expression of circ_0090231; (b) Cell viability; (c) LDH release; (d) IL-1β level; (e) IL-18 level; (f) Cell pyroptosis; and (g) Expression of pro-Caspase 1; cleaved-Caspase 1; GSDMD-N in ox-LDL treated or non-treated HAECs upon transfection with circ_0090231 specific or mock siRNAs. *P < 0.05 versus control, **P < 0.01 versus control, ## P < 0.01 versus control. si-nc, blank vector; si- circ_0090231, knockdown of circ_0090231