Figure 4.

Circ_0090231 sponges miR-635. (a) The binding sites between miR-635 and circ_0090231. (b) The luciferase activity of HAECs cells co-transfected with luciferase reporter vector containing circ_0090231 MREs for miR-635 and miR-635 overexpression vector. (c) The interaction between miR-635 and circ_0090231. (d) Expression of miR-635 in HAECs with circ_0090231 knockdown. (e) Expression of miR-635 in HAECs exposed to ox-LDL vs control cells. **P < 0.01 versus vector, si-NC, biotin-NC or control. si-nc, blank vector; si- circ_0090231, knockdown of circ_0090231