Figure 4.

Anti-tumor activity of nanoparticles loaded with DOX. (a) Inhibition effect of DOX-loaded nanoparticles on tumor volume growth. (b) Image of tumors removed from the mice at the end of treatment. (c) The weight of tumors. (d) The changes of mice body weight during the treatment. Here was the statement that two mice were dead due to individual differences during the treatment, which were removed from the final statistics. (n = 5, data were means ± s.d.). *p < 0.05, **p < 0.01, ***p < 0.001