Figure 8.

Incorporating SkewC with scRNA-seq workflow

(A) Incorporating SkewC in two types of scRNA-seq analysis workflows. Dashed lined indicates process run in R project continues lines represented process that run outside R project (A) analysis of 10xGenomics gene expression dataset. The output from Cell Ranger used as input for SkewC and Surat R package. SkewC annotation added as metadata column to Seurat object.

(B) The second type of scRNA-seq analysis for non 10xGenomics dataset using the SingleCellExperiment class.