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. 2022 Jan 22;25(2):103802. doi: 10.1016/j.isci.2022.103802

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Analysis of LdHP unique genetic features

(A) Summary of LdHP unique genetic changes. Genes with LdHP unique polymorphisms are highlighted across the 36 chromosomes in the genome. Genes in the forward direction are labeled in blue, genes in the reverse direction are labeled in red.

(B) Annotation enrichment analysis of genes with unique polymorphisms in the cutaneous Himachal isolate along the chromosomes with increased ploidy and unequal parental contributions.

(C) Copy number analysis of the A2 gene family. Compared to both the baseline CL-SL and the increased SL-VL strain, the LdHP isolate shows a decrease in A2 gene copy numbers. Raw sequencing depth ratios are shown in the left column and copy numbers extrapolated using four A2 genes in the LdCL reference are shown in the middle column and represented visually in the right side. See also Table S1.