Table 1.
Baseline clinical and demographic data from children included in the CHAT study for both resolution approaches
| OSA | OSAO+C | |||||
|---|---|---|---|---|---|---|
| Resolution | No resolution | P | Resolution | No resolution | P | |
| Subjects (n) | 252 | 152 | — | 157 | 247 | — |
| Age (years) | 6.00 [2.50] | 7.00 [2.50] | 0.07 | 6.00 [2.00] | 6.00 [3.00] | 0.85 |
| Males (n) | 119 (47.6%) | 77 (50.7%) | 0.50 | 73 (46.5%) | 123 (49.8%) | 0.52 |
| BMIz | 0.69 [1.93] | 1.47 [2.07] | <0.001 | 0.66 [2.11] | 1.03 [2.03] | 0.002 |
| AHI (e/h) | 4.80 [5.14] | 8.23 [7.59] | <0.001 | 4.79 [5.90] | 6.61 [6.35] | <0.001 |
| OAHI (e/h) | 3.61 [4.56] | 7.28 [7.44] | <0.001 | 3.77 [5.55] | 5.22 [6.25] | 0.02 |
| AI (e/h) | 2.18 [2.35] | 2.36 [3.32] | 0.07 | 1.95 [2.41] | 2.35 [2.91] | 0.03 |
| OAI (e/h) | 1.00 [1.74] | 1.32 [2.95] | 0.40 | 1.09 [1.96] | 1.09 [2.18] | 0.44 |
| Race (n) | 0.01 | 0.19 | ||||
| White | 105 (41.7%) | 41 (27.0%) | 57 (36.3%) | 89 (36.0%) | ||
| Black | 118 (46.8%) | 97 (63.8%) | 78 (49.7%) | 137 (55.5%) | ||
| Other | 29 (11.5%) | 14 (9.2%) | 22 (14.0%) | 21 (8.5%) | ||
| Heart rate (bpm) | 84.00 [14.00] | 85.00 [13.00] | 0.10 | 84.00 [13.00] | 84.00 [12.75] | 0.95 |
| Tonsil size > 2+ (n) | 197 (78.2%) | 106 (69.7%) | 0.20 | 126 (80.3%) | 177 (71.7%) | 0.06 |
Data are showed as median [interquartile range] or n (percentage).
eAT, early adenotonsillectomy; WWSC, watchful waiting with supportive care; BMIz, body mass index z-score; AHI, apnea-hypopnea index; OAHI, obstructive apnea-hypopnea index; AI, apnea index; OAI, obstructive apnea index; OSA, obstructive sleep apnea; OSAO+C, obstructive and central sleep apnea.
OSA resolution was defined as those subjects who showed an OAHI ≤ 2 e/h and an OAI ≤ 1 e/h at follow-up. OSAO+C resolution was defined as those children who presented an AHI ≤ 2 e/h and an AI ≤ 1 e/h at follow-up.
Statistically significant differences (p < 0.05) have been highlighted in bold.