Table 1.
Patient Characteristics
| Characteristic | Patients without HCC (n=355) |
Patients who developed HCC (n=42) |
p-value* |
|---|---|---|---|
|
| |||
| Age | 52.0 (23.0 – 82.0) | 53.5 (42.0 – 67.0) | 0.32 |
|
| |||
| Sex (% male) | 208 (58.6%) | 30 (71.4%) | 0.13 |
|
| |||
| Race/Ethnicity (%) | 0.27 | ||
| Non-Hispanic White | 324 (91.3) | 36 (85.7) | |
| Non-Hispanic Black | 8 (2.3) | 2 (4.8) | |
| Hispanic White | 7 (2.0) | 2 (4.8) | |
| Asian | 4(1.1) | 1 (2.4) | |
| Other/unknown | 12 (3.4) | 1 (2.4) | |
|
| |||
| Etiology of Liver Disease (%) | 0.83 | ||
| Hepatitis C | 164 (46.2%) | 24 (57.1%) | |
| Alcohol-related | 55 (15.5%) | 6 (14.3%) | |
| NASH/cryptogenic | 71 (20.0%) | 7 (16.7%) | |
| Hepatitis B | 16 (4.5%) | 1 (2.4%) | |
| Other | 49 (13.8%) | 4 (9.5%) | |
|
| |||
| Child Pugh Class (% Child A) | 145 (40.8%) | 14 (33.3%) | 0.41 |
|
| |||
| MELD | 9 (6 – 17) | 10 (6- 17) | 0.32 |
|
| |||
| Number of HCC lesions | N/A | ||
| 1 | N/A | 25 (59.5%) | |
| 2 | 11 (26.2%) | ||
| 3 | 2 (4.8%) | ||
| >3 | 4 (9.5%) | ||
|
| |||
| Maximum HCC diameter | N/A | 2.4 (0.5 – 6.0) | N/A |
|
| |||
| Vascular invasion | N/A | 9 (21.4%) | N/A |
|
| |||
| Extra-hepatic metastases | N/A | 0 (0%) | N/A |
|
| |||
| BCLC Stage | N/A | ||
| Stage 0/A | N/A | 24 (57.1%) | |
| Stage B | 8 (19.0%) | ||
| Stage C | 2 (4.8%) | ||
| Stage D | 8 (19.0%) | ||
|
| |||
| BMI | 28.9 [17.4, 68.6] | 28.6 (20.4 – 50.5) | 0.32 |
|
| |||
| Diabetes | 82 (23.1%) | 7 (16.7%) | 0.44 |
|
| |||
| Presence of Ascites | 211 (59.4%) | 28 (66.7%) | 0.41 |
|
| |||
| Presence of hepatic encephalopathy | 114 (32.1%) | 17 (40.5%) | 0.30 |
|
| |||
| Presence of esophageal varices | 208 (58.6%) | 28 (66.7%) | 0.41 |