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Oncology Reports logoLink to Oncology Reports
. 2022 Jan 27;47(4):62. doi: 10.3892/or.2022.8273

Exosomes derived from Piwil2-induced cancer stem cells transform fibroblasts into cancer-associated fibroblasts

Dan Zhang, Dian Li, Lianju Shen, Dong Hu, Bo Tang, Wenhao Guo, Zhang Wang, Zhaoxia Zhang, Guanghui Wei, Dawei He
PMCID: PMC8848479  PMID: 35088878

Oncol Rep 43: 1125-1132, 2020; DOI: 10.3892/or.2020.7496

Following the publication of the above paper, the authors have realized that they made an error during the assembly of the western blotting data in Fig. 4; essentially, the western blotting data shown for the FAP experiment in Fig. 5 were mistakenly inserted into Fig. 4 to show the metalloproteinase-9 (MMP-9) data.

Figure 4.

Figure 4.

MMP2 and MMP9 expression levels in FBs following incubation with Piwil2-iCSC-Exo (200 µg/ml). GAPDH was used as a loading control. At least three independent experiments were conducted. Results were considered statistically significant at P<0.05 (*P<0.05, **P<0.01 vs. control group; #P<0.05 vs. PBS group). One-way ANOVA and the LSD post hoc test were selected for analysis. FBs, fibroblasts; Piwil2-iCSC-Exo, exosomes derived from Piwil2-induced cancer stem cells; MMP, matrix metalloproteinase.

The authors re-examined their original data, and discovered how the error in the compilation of Fig. 4 arose. The corrected version of Fig. 4, incorporating the correct data for the MMP-9 experiment, is shown below. Note that this error did not affect the overall conclusions reported in the study. The authors are grateful to the Editor of Oncology Reports for allowing them the opportunity to publish this Corrigendum; furthermore, they apologize for any inconvenience caused to the readership of the Journal.


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