Figure 1.

Optimization of extraction condition for new herbal decoctions. (A) GMC (GR and MC) and (B) GMR (GR and MR) were extracted according to the indicated mixing ratios. The mushroom tyrosinase activity was determined using 1 mM L-dopa as the substrate in the absence and presence of each extract. Bar graph (mean ± SEM) data from three experiments were determined using one-way ANOVA with Tukey's post hoc test, ∗∗∗P < 0.001; ∗∗P < 0.01; ∗P < 0.05, compared with the vehicle group.