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. 2022 Feb 16;77:103883. doi: 10.1016/j.ebiom.2022.103883

Table 2.

The comparison of glycosylation between anti-dsDNA IgG and total IgG in treatment-naïve SLE patients.

Anti-dsDNA IgG
Total IgG
N Mean SD N Mean SD P value
Fuc
IgG1 86 0.272 0.094 101 0.277 0.075 0.034
IgG2 86 0.148 0.035 101 0.113 0.028 <0.001
IgG3/4 86 0.295 0.065 101 0.065 0.028 <0.001
Gal
IgG1 86 0.141 0.054 101 0.158 0.051 0.022
IgG2 86 0.023 0.005 101 0.046 0.018 <0.001
IgG3/4 86 0.087 0.026 101 0.028 0.014 <0.001
Bis
IgG1 86 0.044 0.014 101 0.049 0.014 0.013
IgG2 86 0.064 0.023 101 0.018 0.005 <0.001
IgG3/4 86 0.191 0.046 101 0.011 0.005 <0.001
Sia
IgG1 86 0.010 0.005 101 0.011 0.006 0.068
IgG2 86 0.005 0.002 101 0.005 0.002 0.019
IgG3/4 86 0.003 0.001 101 0.003 0.002 0.006

Abbreviations: Fuc: fucosylation; Gal: galctosylation; Bis: bisecting GlcNAc; Sia: sialylation; N: number; SD: standard deviation; IgG: immunoglobulin.