All patients on opioids (A) showed a drop in morphine milligram equivalents per day (MME/day) from 15.1 to 11.0 (n = 186, **p < 0.01). Patients below 15 MME/day (B) showed a drop from 3.5 to 2.1 (n = 134, **p < 0.01). Patients above 15 MME/day pre-medical cannabis (C) showed a drop from 44.9 to 33.9 (n = 52, **p < 0.01). All patients on opioids, patients below 15 MME/day, and patients above 15 MME/day had a 38.7%, 48.5%, and 13.5%, drop to 0 rate, respectively (D). There was no significant difference in change in MME/day between patients with radicular (n = 88), degenerative (n = 81), or deformity (n = 17) etiology of pain (4.7 vs. 3.5 vs. 3.3, p = 0.88) (E).