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. 2022 Feb 15;6(3):286–305. doi: 10.7150/ntno.66556

Table 1.

Radiolabeled molecules or peptides for imaging

Agent Target Class Stage Active clinical trials References
18F- AraG Deoxyguanosine kinase (dGK) Small Molecule Clinical NCT04052412, NCT03142204, NCT04186988, NCT03129061, NCT03684655, NCT03367962 10, 11, 135
18F-CFA dCK Small Molecule Clinical NCT03409419 136
1-L-18F-FETrp IDO Small Molecule Preclinical 137
18F-FAC Deoxycytidine kinase (dCK) Small Molecule Clinical 8
68Ga-WL12 PD-L1
PD-L1
PD-L1
PD-L1
PD-L1
PD-L1
Peptide Preclinical 138
18F-FPy-WL12 Peptide Preclinical 24
18F-NOTA-ZPD-L1_1 Affibody Preclinical 139
64Cu-DOTA-FN3hPD-L1 Adnectin Preclinical 140
68Ga-NOTA-Nb109 Nanobody Preclinical 141
64Cu-DOTA-HAC-PD1 High-affinity PD-1 ectodomain Preclinical 142, 143