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. 2022 Jan 20;10(2):217. doi: 10.3390/biomedicines10020217

Table 5.

Blood levels of explorative parameters for study collectives, median (IQR).

Parameter Healthy (n = 29) PAD (n = 40) AAA (n= 40) p-Value (Groups)
citH3 (ng/mL) 292.3 (83.6) 296.4 (221.7) 353.2 (263.3) * 0.046 (H/AAA)
0.734 (H/PAD)
0.070 (PAD/AAA)
MPO (ng/mL) 7.51 (3.20) 12.11 (5.60) 14.47 (11.74) <0.001 (H/AAA)
<0.001 (H/PAD)
0.021 (PAD/AAA)
cfDNA (RU) 0.277 (0.217) 0.311 (0.190) § 0.437 (0.737) § 0.002 (H/AAA)
1.000 (H/PAD)
0.003 (PAD/AAA)
oxPL/apoB (RU) 6.33 (104.08) 43.42 (92.50) 0.00 (39.00) # 0.197 (H/AAA)
0.181 (H/PAD)
0.001 (PAD/AAA)

p-values refer to group comparisons between the healthy (H), abdominal aortic aneurysm (AAA) and peripheral artery occlusive disease (PAD) collectives by Mann–Whitney U test. cfDNA, cell-free DNA; citH3, citrullinated histone H3; MPO, myeloperoxidase; oxPL/apoB, oxidized phospholipid/apolipoprotein B-100 complexes; RU, relative units; * n = 38, § n = 30, # n = 39.