Figure 3.

Assessment of the overall activity and anxiety-like behavior with the open-field test (OFT). All the mice were subjected to the OFT during week 7, and their activity was recorded for 10 min. The distance (A), speed (B), total time immobile (C), number of immobile episodes (D), number of center zone entries (E), and time spent in the center zone (F) were analyzed using the ANY-maze software from the recording. Each bar indicates the group average ± SEM (n = 10 per group). Red open circles and blue diamonds represent individual values for the sham and BLG mice, respectively. The numbers between the two bars indicate the p-values. Statistical significance (p < 0.05) was determined using an unpaired Student’s t-test.