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. 2022 Feb 21;14(2):444. doi: 10.3390/v14020444

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Changes in parvovirus B19 (B19V) viral RNA following 6 months IFN-ß treatment (determined as copies/μg). Patients received placebo are shown in red. B19V viral RNA was significantly reduced in IFN-ß treated patients from baseline to follow-up (p = 0.001). No significant difference was seen at baseline between INF-b treated and placebo patients (p = 0.3). In contrast, at follow-up IFN-ß treated and placebo patients differ significantly (p = 0.0005). Nonparametric Wilcoxon-Mann-Whitney-Test was used to compare the results at the two time points (before vs. after treatment) and between the groups. B19V: parvovirus B19; IFN-ß: interferon beta-1b; RNA: ribonucleic acid.