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. 2022 Feb 4;14(2):362. doi: 10.3390/pharmaceutics14020362

Table 1.

Representative examples and the physical properties of chromophores with photoacoustic properties that have been used within cancer theranostics. The name of the chromophore, its chemical structure, its maximum wavelength of absorption (λab (nm)) and emission (λfl (nm)), the molar extinction coefficient (ε, (M−1 cm−1)), and the fluorescence quantum yield (Φ) are presented.

Dye Chemical Structure λab (nm) λfl (nm) Εmax (M−1 cm−1) Φ Ref.
Protoporphyrin IX graphic file with name pharmaceutics-14-00362-i001.jpg 405 635 40,603 <0.01 (±0.01)
in water
[75]
Methylene Blue graphic file with name pharmaceutics-14-00362-i002.jpg 665 691 95,000 0.52
in ethanol
[76]
Indocyanine Green graphic file with name pharmaceutics-14-00362-i003.jpg 779
(in water)
815
(in blood)
805
(in water)
815
(in blood)
156,000 ± 6000 2.9 ± 0.2
(in water)
13 ± 1
(in blood)
[77]
PyBODIPY-7 graphic file with name pharmaceutics-14-00362-i004.jpg 734 below the device detection limit 55,800 17 [78]