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. 2022 Jan 20;14(2):241. doi: 10.3390/pharmaceutics14020241

Table 3.

EGFR-targeted PDT performed with anti-EGFR peptides.

Targeting Agent PS In Vitro Studies In Vivo studies Ref.
LARLLT Zinc phthalocyanine (ZnPc) A431, MCF-7 A431 cells in female BALB/c nude mice [105]
YHWYGYTPQNVI Chlorin e4 (Ce4) PCA-SMCs,
MDA-MB-231,
MDA-MB-468, HCC70
MDA-MB-468 cells in mice [106,107]
KLARLLT Zinc
phthalocyanine (ZnPc)
A431, A549, MCF-7, PC-3 A431 cells in BALB/c female nude mice [108]
YHWYGYTPQNVI Zinc phthalocyanine (ZnPc) A431, MCF-7 A431 cells in BALB/c female nude mice [109]
QRHKPREGGGGSK Zinc phthalocyanine (ZnPc) HT29, HEK-293, HepG2 HT29 cells in female Balb/c nude mice [110]
Cyclic CMYIEALDKYAC Zinc phthalocyanine (ZnPc) HT29, HCT116, HeLa, HEK293 HT29 cells in female Balb/c nude mice [111]