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pH dependence of the relative folding energy of S protein RBDs of SARS-CoV and SARS-CoV-2. All values are the differences to the folding energy values at pH = 0, which means that positive values indicate that the energies are higher than the folding energy at pH = 0, and negative values indicate that the energies are lower than the folding energy at pH = 0. So, the larger absolute value is, the larger difference is.
