REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
α-Synuclein (αSyn)	Abcam	(Cat# ab51252, RRID:AB_869971)
pSer129 α-Synuclein (Rabbit monoclonal)	Abcam	(Cat# 2014-1, RRID:AB_765074
anti-GATA2 (Mouse polyclonal)	R and D systems	Cat# MAB2046, RRID:AB_2108424)
anti-β-actin (Mouse monoclonal)	Santa Cruz Biotechnology	Cat# sc-47778 HRP, RRID:AB_2714189
anti-aggregated αSyn	Abcam	(Cat# ab209538, RRID: AB_2714215
Bacterial and virus strains
Akkermansia muciniphila	DSMZ	DSM 22959, Type strain
E.coli	ATCC	ATCC 25922
Biological samples
Human fetal brain cDNA library	Clontech	Cat# HL3003a
Chemicals, peptides, and recombinant proteins
Fluo-4/AM	Thermo-Fisher	F14201; CAS#: 273221-67-3
Rhod-2/AM	Thermo-Fisher	R1245M; CAS#: 145037-81-6
Dihydroethidium (Hydroethidine)	Thermo-Fisher	D11347; CAS# 38483-26-0
Mucin from porcine stomach	Sigma-Aldrich	M2378; CAS#: 84082-64-4
Thapsigargin	Sigma-Aldrich	240117; CAS: 629-11-8
FuGene HD	Promega	E2311
Dantrolene Sodium Salt	Sigma-Aldrich	D9175; CAS# 14663-23-1
MitoTracker Red CMXROS	Thermo-Fisher	M7512; CAS#: 167095-09-2
Critical commercial assays
Cholecystokinin EIA Kit	Sigma-Aldrich	RAB0039
CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS)	Promega	G3582
Experimental models: Cell lines
STC-1	ATCC	(Cat# CRL-3254, RRID:CVCL_J405)
Experimental models: Organisms/strains
FVB Mus musculus	The Jackson Laboratory	N/A
Oligonucleotides
Primer: HsSnca.M1 forward: 5′- CATCTAAGC TTGCCATGGATGTATTCATGAAAGGAC -3′; reverse: 5′-ATGACACCCGGGGGCTTCAGG TTCGTAGTCTTGATAC -3′;	This paper	N/A
Primer: Akkermansia muciniphila AM1: 5′- CAGCACGTGAAGGTGGGGAC -3′; AM2: 5′- CCTTGCGGTTGGCTTCAGAT -3′	(Collado et al., 2007)	N/A
Recombinant DNA
Plasmid: pAc1GFP1-Parvalbumin-GFP	(Guerra et al., 2011)	6084-1
Plasmid: pAc1GFP1-Parvalbumin-Mito-GFP	(Guerra et al., 2011)	632524
Plasmid: pcDNA5mCherry-hαSyn	This paper	N/A
Plasmid: pEGFP-hαSyn	This paper	N/A
Plasmid: pEGFP-C1	Addgene	6084-1
Plasmid: pmCherry-C1	Addgene	632524
Software and algorithms
Image J	(Schneider et al., 2012)	https://imagej.nih.gov/ij/
Graphpad Prism 8	GraphPad Software, Inc	https://www.graphpad.com/scientific-software/prism/
MaxQuant 1.3	Max-Planck-Institute of Biochemistry	https://www.maxquant.org/