Long-Term Metabolic Correction of Phenylketonuria by AAV-Delivered Phenylalanine Amino Lyase

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(Molecular Therapy: Methods & Clinical Development, 19, 507–517; December 2020)

In the originally published version of this article, there was an unintended error in Figure. 3C. In particular, left panels of Figure. 3C (immunostaining images showing avPAL expression in PBS-injected female mice) were duplications of left panels Figure 2D (images showing avPAL expression in PBS-injected male mice). In order to correct these mistakes, the authors re-examined the raw data for immunostaining. With these raw data, the authors have now generated the correct Figure. 3C. Noteworthy, this correction does not affect the interpretation and the conclusions of the manuscript. The authors regret this error.

Figure 3. A Single Dose of AAV8-PAL Corrected Hyperphenylalaninemia in Female PKU Mice