Table 3.
Multivariate odds of transition from pre-DM to DM among the 1584 pre-DM men
| MODEL A | MODEL B | |||||
|---|---|---|---|---|---|---|
| Variable | PWOH+PWH OR (95% CI), P |
PWOH OR (95% CI), P |
PWH OR (95% CI), P |
PWOH+PWH OR (95% CI), P |
PWOH OR (95% CI), P |
PWH OR (95% CI), P |
| Seropositive for HIV [ref = Seronegative] | 1.4 (1.0, 1.8), 0.04 | - | - | 1.2 (0.9, 1.6), 0.22 | - | - |
| Age, per 10 years | 1.1 (0.9, 1.3), 0.38 | 1.0 (0.8, 1.2), 0.73 | 1.3 (1.0, 1.7), 0.051 | 1.0 (0.8, 1.2), 0.87 | 0.9 (0.7, 1.1), 0.47 | 1.2 (0.9, 1.5), 0.22 |
| Number of previous pre-DM to DM transitions | 3.9 (2.9, 5.1), <0.01 | 3.4 (2.6, 4.5), <0.01 | 7.0 (3.4, 14.2), <0.01 | 3.8 (2.8, 5.1), <0.01 | 3.4 (2.6, 4.4), <0.01 | 7.5 (3.3, 17.2), <0.01 |
| Non-white [ref = Non-Latino white] | 1.2 (0.9, 1.6), 0.29 | 1.3 (0.8, 2.1), 0.27 | 1.5 (1.0, 2.3), 0.048 | 1.2 (0.9, 1.7), 0.18 | 1.4 (0.8, 2.2), 0.19 | 1.6 (1.1, 2.5), 0.03 |
| Last measure seropositive for HCV [ref = Last measure seronegative] | 1.3 (0.8, 2.1), 0.36 | 1.4 (0.8, 2.8), 0.27 | 1.0 (0.4, 2.3), 0.98 | 1.2 (0.7, 2.0), 0.45 | 1.3 (0.7, 2.7), 0.43 | 0.9 (0.4, 2.0), 0.83 |
| BMI, per five kg/m2 | 1.5 (1.3, 1.7), <0.01 | 1.5 (1.3, 1.7), <0.01 | 1.6 (1.4, 2.0), <0.01 | 1.3 (1.2, 1.5), <0.01 | 1.4 (1.2, 1.7), <0.01 | 1.4 (1.1, 1.8), <0.01 |
| Family history of diabetes [ref = No family history] | 1.7 (1.3, 2.3), <0.01 | 2.0 (1.3, 2.9), <0.01 | 1.3 (0.9, 1.9), 0.20 | 1.7 (1.3, 2.3), <0.01 | 2.0 (1.3, 3.0), <0.01 | 1.3 (0.9, 2.0), 0.18 |
| Waist-hip ratio, standardized | - | - | - | 1.3 (1.1, 1.5), <0.01 | 1.2 (0.9, 1.4), 0.19 | 1.4 (1.1, 1.6), <0.01 |
| Examiner-assessed lipoatrophy [ref = No lipoatrophy] | - | - | 2.2 (1.1, 4.4), 0.02 | - | - | 2.3 (1.2, 4.5), 0.02 |
| Duration of HIV infection, per five years | - | - | 0.8 (0.7, 1.0), 0.07 | - | - | 0.8 (0.7, 1.0), 0.03 |
| History of AIDS [ref = No history] | - | - | 2.9 (1.7, 5.0), <0.01 | - | - | 2.8 (1.6, 4.8), <0.01 |
| Cumulative HIV viral copy-years after baseline, per 1,000,000 copy-years | - | - | 0.2 (0.0, 1.5), 0.10 | - | - | 0.2 (0.0, 1.7), 0.13 |
| Cumulative years of stavudine use, per five years | - | - | 1.3 (1.0, 1.7), 0.09 | - | - | 1.3 (1.0, 1.7), 0.10 |
| Cumulative years of NRTI use, per five years | - | - | 1.2 (0.9, 1.5), 0.17 | - | - | 1.2 (0.9, 1.5), 0.26 |
| Cumulative years of PI use, per five years | - | - | 1.1 (0.9, 1.3), 0.34 | - | - | 1.1 (0.9, 1.4), 0.16 |
| Thymidine analog use [ref = No thymidine analog use] | - | - | 1.6 (1.0, 2.5), 0.03 | - | - | 1.7 (1.1, 2.6), 0.02 |
Model A: multivariate transition model with odds of transition from pre-DM to DM among pre-DM PWOH and PWH adjusted for traditional risk factors. Model B: multivariate transition model with odds of transition from pre-DM to DM among pre-DM PWOH and PWH adjusted for traditional risk factors plus waist-hip ratio.